NFL Scores
Loading scores…
Back to CFB Predictions
COLLEGE FOOTBALL
WEEK 2
ESPN+AI Prediction

SEMO @ Iowa State Cyclones

Saturday, September 5, 2026

AI Condition Layer Analysis

XGBoost ML model trained on 2019–2025 CFB seasons · 70% confidence

Iowa State CyclonesWIN PROBABILITYSoutheast Missouri State Redhawks
59%
41%

MODEL PICK

Iowa State Cyclones

CONFIDENCE

70%

5

Home Edge

2

Neutral

0

Away Edge

Condition Layers (7 factors analyzed)

Cyclones 60/10050/100 Redhawks

Iowa State Cyclones

60/100 — 41-34 over 6 seasons

Southeast Missouri State Redhawks

50/100 — 36-36 over 6 seasons

Iowa State Cyclones rates 60/100 vs SEMO at 50/100 — a 10-point gap in program quality.

Cyclones 0/1000/100 Redhawks

Iowa State Cyclones

0-0 (0% win rate)

Southeast Missouri State Redhawks

0-0 (0% win rate)

Iowa State Cyclones is 0-0 vs SEMO at 0-0 this season.

Series History (2019–2024)

42
2024
Cyclones wins4420
2023
SEMO wins2210
2022
SEMO wins4415
2021
Cyclones wins3423
2020
Cyclones wins2313
2019
Cyclones wins259

6-Season Program History (2019–2024)

Iowa State Cyclones

41-34 overall
2019
7-6
2020
9-3AP #10
2021
7-6
2022
4-8
2023
7-5
2024
7-6

AP Ranked in 1 of 6 seasons

Southeast Missouri State Redhawks

36-36 overall
2019
6-6
2020
6-6
2021
6-6
2022
6-6
2023
6-6
2024
6-6

AP Ranked in 0 of 6 seasons

About this model: Predictions are generated by an XGBoost machine learning model trained on 6+ years of college football data (2019–2025), including win/loss records, scoring offense/defense, AP rankings, strength of schedule, home field advantage, and head-to-head matchup history. Model historical accuracy: ~68%. For entertainment purposes only.

Game Information

Kickoff

Sat, Sep 5, 5:00 PM UTC

Network

ESPN+

Stadium

Jack Trice Stadium