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COLLEGE FOOTBALL
WEEK 2
ESPN+AI PredictionSEMO @ Iowa State Cyclones
Saturday, September 5, 2026
AI Condition Layer Analysis
XGBoost ML model trained on 2019–2025 CFB seasons · 70% confidence
Iowa State CyclonesWIN PROBABILITYSoutheast Missouri State Redhawks
59%
41%
MODEL PICK
Iowa State Cyclones
CONFIDENCE
70%
5
Home Edge
2
Neutral
0
Away Edge
Condition Layers (7 factors analyzed)
Cyclones 60/10050/100 Redhawks
Iowa State Cyclones
60/100 — 41-34 over 6 seasons
Southeast Missouri State Redhawks
50/100 — 36-36 over 6 seasons
Iowa State Cyclones rates 60/100 vs SEMO at 50/100 — a 10-point gap in program quality.
Cyclones 0/1000/100 Redhawks
Iowa State Cyclones
0-0 (0% win rate)
Southeast Missouri State Redhawks
0-0 (0% win rate)
Iowa State Cyclones is 0-0 vs SEMO at 0-0 this season.
Series History (2019–2024)
4–2
2024
Cyclones wins44 – 20
2023
SEMO wins22 – 10
2022
SEMO wins44 – 15
2021
Cyclones wins34 – 23
2020
Cyclones wins23 – 13
2019
Cyclones wins25 – 9
6-Season Program History (2019–2024)
Iowa State Cyclones
41-34 overall2019
7-6
2020
9-3AP #10
2021
7-6
2022
4-8
2023
7-5
2024
7-6
AP Ranked in 1 of 6 seasons
Southeast Missouri State Redhawks
36-36 overall2019
6-6
2020
6-6
2021
6-6
2022
6-6
2023
6-6
2024
6-6
AP Ranked in 0 of 6 seasons
About this model: Predictions are generated by an XGBoost machine learning model trained on 6+ years of college football data (2019–2025), including win/loss records, scoring offense/defense, AP rankings, strength of schedule, home field advantage, and head-to-head matchup history. Model historical accuracy: ~68%. For entertainment purposes only.
Game Information
Kickoff
Sat, Sep 5, 5:00 PM UTC
Network
ESPN+
Stadium
Jack Trice Stadium